The work describes the theoretical and methodological foundations and results of a study of the labor potential of the Vologda region, analyzes the quantitative and qualitative side of the region’s labor potential, considers the possibilities of managing labor resources and labor potential at the regional level, describes the results of measuring partial and integral indices of the quality of labor potential, an analysis of their dynamics and compliance with the requirements of workplaces is given, an assessment is made of the relationship between the quality of labor potential and the effectiveness of labor activity. The book is intended for researchers, teachers, graduate students, as well as everyone interested in the problems of measuring and developing the labor potential of the region.