Gideon Crewe - a brilliant scientist and former thief - is once again taking on the task of his mysterious employer Eli Glynn. Gideon's mission: to steal a page from the priceless Book of Kells, displayed as an exhibit in New York and protected by an unbreakable security system. Gideon manages to steal the parchment - only to discover that hidden beneath the magnificent image is a treasure map dating back to the days of the ancient Greeks. Pondering over the strange map, Gideon and his employers realize that the treasure it leads to is truly priceless: an amazing discovery that could even save many lives, including Gideon's own. Together with his partner named Amy, Gideon sets off along an unknown route to a remote corner of the Caribbean. There, off the hostile and desolate Mosquito Coast, the pair realize that the extraordinary treasure they are hunting hides an even older secret - a revelation so profound that it could benefit the entire human race... if Gideon and Amy survive, of course.