Eight years ago, Joseph Miles set out in search of a cure for the disease that he believed had turned him into a monster. The result was a series of bloody murders that left a trail of dismembered and eaten corpses from San Francisco to Seattle. After being convicted and sentenced to life in prison, Joseph is still searching for a cure. But he can't find what he's looking for while behind bars. With the help of a lone guard and a young model, he tries to escape from prison. But his accomplices may have completely different plans for him...