The Python 3 language is described: data types, operators, conditions, loops, regular expressions, functions, object-oriented programming tools, working with files and directories, frequently used modules of the standard library. The basics of the SQLite database, the database access interface, and methods for retrieving data from the Internet are presented. Particular attention is paid to the PyQt 5 library, which allows you to create applications with a graphical interface in Python. Tools for processing signals and events, managing window properties, developing multi-threaded applications are considered, the main components (buttons, text fields, lists, tables, menus, toolbars, etc.), options for their placement inside the window, tools for working with databases are described. , multimedia, printing documents and exporting them in Adobe PDF format. All examples from the book are provided on the publisher’s website.