The textbook was written by teachers of the Department of Faculty Therapy of the St. Petersburg Pediatric Medical Academy with the participation of employees of the city multidisciplinary hospital No. 2 of St. Petersburg. The book is a systematic questionnaire on the main sections of internal medicine. Each question is followed by a specific answer, combining background information with modern aspects of the problem being discussed. The structure of the book allows it to be used both for self-study and for self-control on the material presented. The textbook complies with the program approved by the Ministry of Health of the Russian Federation and is intended for students of medical higher educational institutions.