This manual is intended for the study of propaedeutics and private pathology of internal diseases in the III course of the faculties of training doctors. The purpose of the book is to promote the mastery of the basics of medical activity: the method of examining a patient, the semiotics of diseases of internal organs, the ability to recognize the main clinical manifestations of diseases, as well as the development of skills in making a diagnosis, which is necessary for a doctor of any specialty.The content and volume of the manual correspond syllabus on propaedeutics of internal diseases and therapy for the 3rd year of faculties of medical training.The third edition contains modern classifications of internal diseases, updated illustrations demonstrating electrocardiographic, radiological and ultrasound phenomena, practical advice on the use of various examination methods in special clinical cases.