Bleeding and thrombosis is two component parts, two poles of гемостаза in the coagulant system of man. Knowledge of bases of physiology of the coagulant system, estimation of the state and factors, influencing on риски of origin of bleeding or thromboses, possibilities of correction need to every clinician in everyday practice.This book is a result of efforts of experts in the different areas of medicine - from physiology and laboratory diagnostics before a reanimation and эндоваскулярной surgery. An aim that was pursued by authors is an attempt to make the integral impression about the system of hemopexis - from general presentation to the private questions with that clinicians clash in everyday practice.At the end of manual tables and situatioonal tasks that will allow to the reader to apply the stated data in concrete clinical situations are presented.Edition it is counted on the wide circle of specialists, mainly surgeons and general practitioners.