AD 64 — Roman centurion Marcus Domitus leads an expedition to find the mythical treasure hidden deep inside Queen Dido's temple.

AD 1945 — In the confusion and chaos of a burning Berlin, two high-powered Nazis disappear, and so does a precious object.

AD 2009 — Two families are brutally tortured and murdered in Boston and London, the crimes linked by a single name and a shared history.

Art recovery specialist Jamie Saintclair receives a call from a Boston detective, asking for his help to investigate a brutal murder. She believes Saintclair might hold the key to solving the crime through his detailed knowledge of specialist Nazi units. But as they delve deeper into the sinister world of the occult, they uncover a dark secret that men have lusted over for more than two millennia. Long ago, in the ancient temple of Isis, something was stolen, and the repercussions have resonated through the centuries. Saintclair must discover the truth before the curse claims more victims, and finally catches up with him.