This textbook first appeared in early 2007 and has been used by numerous students and practitioners and in many courses, including our own experience teaching this material both online and in person for more than 15 years. The first edition, based on the Excel add-in Analytic Solver Data Mining (previously XLMiner), was followed by two more Analytic Solver editions, a JMP edition, an R edition, and now this Python edition, with its companion website,www.dataminingbook.com.This new Python edition, which relies on the free and open-source Python programming language, presents output from Python, as well as the code used to produce that output, including specification of the appropriate packages and functions, the dominant one being scikit-learn. Unlike computer-science or statistics-oriented textbooks, the focus in this book is on data mining concepts, and how to implement the associated algorithms in Python. We assume a basic familiarity with Python.For this Python edition, a new co-author, Peter Gedeck comes on board bringing extensive data science experience in business. In addition to providing Python code and output, this edition also incorporates updates and new material based on feedback from instructors teaching MBA, MS, undergraduate, diploma, and executive courses, and from their students as well. Importantly, this edition includes for the first time an extended section on Data Ethics (Section 2.9).A note about the book’s title: The first two editions of the book used the title Data Mining for Business Intelligence. Business Intelligence today refers mainly to reporting and data visualization (“what is happening now”), while Business Analytics has taken over the “advanced analytics,” which include predictive analytics and data mining. In this new edition, we therefore use the updated terms.This Python edition includes the material that was recently added in the third edition of the original (Analytic Solver based) book:Social network analysisText miningEnsemblesUplift modelingCollaborative filteringSince the appearance of the (Analytic Solver based) second edition, the landscape of the courses using the textbook has greatly expanded: whereas initially, the book was used mainly in semester-long elective MBA-level courses, it is now used in a variety of courses in Business Analytics degrees and certificate programs, ranging from undergraduate programs, to post-graduate and executive education programs. Courses in such programs also vary in their duration and coverage. In many cases, this textbook is used across multiple courses. The book is designed to continue supporting the general “Predictive Analytics” or “Data Mining” course as well as supporting a set of courses in dedicated business analytics programs.A general “Business Analytics,” “Predictive Analytics,” or “Data Mining” course, common in MBA and undergraduate programs as a one-semester elective, would cover Parts I–III, and choose a subset of methods from Parts IV and V. Instructors can choose to use cases as team assignments, class discussions, or projects. For a two-semester course, Part VI might be considered, and we recommend introducing the new Part VII (Data Analytics).