"A Serious Suggestion for Ladies to Develop Their True and Highest Interest" is an important feminist work in two parts by Mary Estelle. The book offers innovative views on the status and rights of women in the society of its time. The author calls women to self-improvement, independence and development of their personality. Using the arguments of scientific research and religious interpretations, Mary Estelle proves the importance of education and independent thinking for women. This book was an important step in the struggle for women's rights and intellectual freedom and remains relevant today.