"An Account of the Mode of Inoculating Small-pox in the East: With Some Observations on the Practice and Treatment of that Disease in Those Places" is a book written by John Zephaniah Holwell, which constitutes a valuable document on the methods of preventing and treating small-pox in the East Indies. The author describes in detail the technique of smallpox inoculation carried out in this region, and also gives observations on the effectiveness of this method and the methods of smallpox treatment used in the East. This book allows for a better understanding of the history of medicine and methods of fighting smallpox in the past, helping modern researchers and doctors to improve their knowledge and methods.