"On the Mode of Spread of Cholera" is an outstanding scientific work by the famous English doctor and scientist John Snow. In this book, the author investigates the spread of the cholera epidemic in London and concludes that the disease is transmitted through contaminated water. Snow conducted an extensive epidemiological study using maps and statistics that proved to be a turning point in the investigation of cholera. Not only was this book pivotal in the investigation of cholera, but it also pioneered the use of cartography in medical research. Its importance in the history of medicine and public health is difficult to overestimate.