Man has changed throughout his history. Living conditions and culture changed the fastest, instinctive programs slower, anatomy and physiology - over generations. But biologically, man also changed. Since the middle of the 19th century, with the advent of urban machine civilization, human life has changed dramatically. At the beginning of the 20th century, a hundred years ago, no more than 10-15% of the world's population lived in civilized conditions. Almost everyone lives today. We often don’t even imagine what tremendous opportunities civilization has given us. The person living in it is equal in wealth and power not even to emperors and the highest nobility, but to pagan deities. After all, not a single pharaoh or emperor of Ancient Rome could fly in an airplane or use a mobile phone. The new way of life not only gave enormous wealth and doubled life expectancy, but also caused a number of rapid changes in psychology, physiology, and even human anatomy . Changes are happening faster and faster. Our descendants will differ from us even more than we differ from our ancestors. We are the grandfathers of people who live 130–150 years and become adults by the age of 30–40. And to possess information and energy comparable to everything that any Great Power of the 19th century owned.