The book "Permission to destroy life unworthy of existence. Its measure and form; second edition" highlights an important ethical and sociological aspect - the question of the process of eugenics and its impact on society. Authors Carl Binding and Alfred Hoche comprehensively consider the problem of selection of "unworthy life" for its further eugenic removal. The book raises difficult questions about humane treatment of vulnerable population groups and the danger of abusing such concepts. The second edition presents new research and arguments that broaden the understanding of this issue and call for informed behavior in the field of bioethics.