A wild child of the bayous, Leon Grosvenor is a two-legged freak show of shaggy hair and talons with an insatiable hunger for raw flesh. His unique abilities as a bona fide loup-garou have earned him gainful employment as a contract killer for Cajun mafia boss Armand "Big Crawdaddy" Fortier.

Remo's not buying this werewolf business, but when he gets a glimpse of good ol' Leon§s wet work, well, he's still not a believer, but he is certain that Leon needs to be put out of everybody's misery. And damn soon. The swamps stink, Mardi Gras is giving him a headache and all this talk about silver bullets is getting tedious. But as Leon and his pack circle ever closer to the Destroyer, the question remains: Who is the hunter... and who is dog meat?