When talking about the history of medicine and the discoveries that made it possible to successfully treat diseases, we always remember the names of brilliant doctors and scientists. But we forget about those who made these discoveries possible. Luc Perino's book is dedicated to patients whose cases moved medicine forward and made it what we know today. An interesting adventure awaits you over several centuries, during which you will become an observer of the first experiments with anesthesia, vaccine trials, the treatment of hysteria and other medical events. The author of "Patient Zero" talks about those people who patiently, in rural hospitals or at appointments with medical practitioners, provided their bodies for research. Perhaps not all of them fully understood the contribution they made to the development of medicine, but it was their participation that made the treatment of many diseases effective and successful.