Moonside is a small port town in Maine, most of whose residents are non-human. Under the guise of mere mortals, zombies and ghosts, werewolves, vampires, magicians, elves and demons live here. Yvaine Lovestein must continue the family tradition and, on the day she comes of age, together with the supreme demon Kavi, begin reigning in Moonside, otherwise the city will disappear from the face of the earth. Returning after four years of wandering, Yvaine realizes that the city has changed a lot: the entire magical population of Moonside wants her dead, people are disappearing for unknown reasons, and Kavi, the demon who raised her, has absolutely no memory of Yvaine or the existence of the magical part of Moonside. Now, to fulfill her destiny, Yvaine must rely only on herself.