Children left without parental care and raised in boarding schools represent a high-risk group for developing deviations in health and development. Many of them have perinatal damage to the central nervous system, various somatic disorders, and are born premature. This necessitates the need for timely, adequate rehabilitation interventions in the orphanage. The manual covers in detail modern technologies for the rehabilitation of children with disabilities, as well as those with various somatic disorders. The manual is intended for medical and teaching staff of orphanages, adoptive parents and guardians of orphans.