Max Carter, a young dotcom millionaire, is a space tourist enjoying his stay on the International Space Station. His euphoria rapidly turns to horror as he witnesses the surface of the Earth devastated by nuclear strikes. Stranded on the station, Carter together with the five multinational crewmembers of Expedition 79 are faced with a seemingly hopeless situation. The crew must overcome challenges of dwindling supplies, a disastrous collision with space debris, a fire on board, a crewman with murderous intentions and keeping their very sanity in the face of overwhelming adversity.