The plot concerns the relationship between Eugene Eyestones, the writer of an advice column called "The Sexual Intellectual", and his editor's ex-wife, Laura Warholic, whom Eyestones pities more than likes. This basic story provides the jumping off point for Theroux's satire of American culture.Eugene Eyestones, an erudite sex columnist for a Boston cultural magazine, becomes enmeshed in the messy life of a would-be artist named Laura Warholic. Repulsing and fascinating him at the same time, she becomes a mirror in which he not only sees himself but through which he is forced to face his own demons. Not only does she inadvertently supply him with material for his columns, she represents all Eugene considers to be wrong with contemporary America - a garish and dunce-filled Babylon that Theroux scorches with relentless satire