A book consists of the detailed answers for 100 questions, most often arising up in practice of specialist on a high-efficiency liquid chromatography (ВЭЖХ), working in the laboratory of control quality. Топ-100 of questions made on the basis of long-term experience of author in methodical and technical support of users of ВЭЖХ of equipment and columns.The brought information over closes 80лучаев appeals in service and methodical services of suppliers of ВЭЖХ of equipment, allowing to the users easily to decide all questions own forces.A book fully replaces by itself all existent ВЭЖХ courses of initial level, as gives answers for all typical questions understood the on them, thus the information presented in a book is more detailed and given at higher professional level.Exposition is conducted in form the dialogue of conditional user with conditional by a specialist on technical or methodical support| similar approach facilitates perception of material of book and does the process of reading not only useful but also enthralling.