At the beginning of our century, along with the revolution in the field of physics and chemistry and the further development of mathematics, we observe a significant lag in medical science. In medicine we are still in the pre-revolutionary period. One concept replaces another. For decades, medicine has been working hard, but without a clearly defined plan, not methodically, rushing into one trend and then into another. True science is not only the accumulation of individual facts, it is, first of all, the knowledge of relationships and certain biological laws. It must be emphasized that the volume of the unknown in medicine exceeds the volume of the known. The difficulties of the medical art arise to a much lesser extent from the lack of effective means than from their use itself. We need to balance our scientific knowledge - to understand our needs, what has already been finally achieved and what we do not yet know. [table in Chapter. 7 book 1 is not fully recognized, there is no table 7 of appendix 1]