A sweeping, devastating portrait of three generations of the philanthropic Sackler family, whose fortune was built on Valium and whose reputation was destroyed by OxyContin.

The history of the Sackler dynasty is rife with drama - bitter disputes over estates, brawls in boardrooms , brilliant art collections, Machiavellian maneuvers in court, the calculated use of money to enhance reputations and destroy less powerful people. They are one of the richest families in the world, but the source of the family fortune was murky - until it was revealed that the Sacklers were responsible for the production and marketing of the painkiller drug that catalyzed the opioid crisis.

It's a three-generation saga one family and the mark they will leave on the world. This story travels from the bustling streets of early 20th-century Brooklyn to the seaside palaces of Greenwich and the corridors of power in Washington DC. The book details the numerous investigations into the Sacklers and their company, as well as the scorched earth legal tactics the family used to evade accountability.

Patrick Radden Keefe is an investigative journalist and writer for The New Yorker, author of the bestselling To Say Nothing: A True Story of Murder and Memory in Northern Ireland, which won the National Book Critics Circle Award for Nonfiction and was named one of the Top 10 Best Books of 2019 by The New York Times Book Review, The Washington Post , Chicago Tribune and The Wall Street Journal, and was named one of the "10 Best Non-Fiction Books of the Decade" by Entertainment Weekly.